May 23-24, 2018
St. Louis, MO

Day One
Wednesday May 23, 2018

Day Two
Thursday May 24, 2018

08.50
Chair’s Opening Remarks


Building a Discovery Therapeutics Platform to Identify Novel Targets


Synopsis

Introduction and Purpose:
Despite the current focus on probiotics in animal feed, advanced translational microbiome research could also lead to a new category of animal pharmaceuticals, which represents an exciting market opportunity. Many emerging biotech organizations are beginning to leverage the power of emerging technologies to identify, culture and develop new bacterial strains and generate a scientific foundation to create breakthrough therapeutics. The purpose of this theme will be to outline cutting edge organizations who are investigating the animal microbiome to develop breakthrough therapeutics.

09.00
Novel Therapeutic Discovery in Animal Health

Synopsis

  • Application of metagenomic methods in animal health
  • Signatures of microbiome dysbiosis during infection
  •  Discovery of therapeutic strains using multi-omic approaches

09.30
From Microbiome to Medicine: A New Innovation Platform, Dedicated to Animal Health

10.00
Panel Discussion: Product Development & Registration of Live Bio Therapeutics in Animal Health

Synopsis

• What are the main scientific and commercial challenges when bringing microbiome products to the animal market?
• How are these new modalities different from small molecule compounds within a regulatory setting? How can organizations accelerate shared learning between key stakeholders?
• Where can leading animal health organizations support product development for start-ups?

10.30
Morning Refrements & Networking


Navigating Regulatory Uncertainty – A Hurdle to Successful Application of the Microbiome


Synopsis

Introduction and Purpose:
With regulatory pressures on the use of antibiotic growth promoters increasing in the US, many organisations are looking to find a new process to go from exploratory studies in the animal microbiome to a fully marketed product. With a number of successful case studies in pre- and pro- biotics, the purpose of this theme will be to review current regulatory thinking on natural strategies built around modulation of the animal microbiome that prevent disease.

11.00
A History of Regulating Animal Health Products: Adapting Effectively for the Microbiome


Patentability of the Animal Microbiome


Synopsis

Introduction and Purpose:
With several promising efforts to manipulate microbial communities within animal health, there has been a significant increase in the need for clear and effective intellectual property protection. Though a number of microbiome-focused organizations have built significant patent portfolios to protect product development, the purpose of this theme will be to review the main concerns and strategies in patent law when dealing with microbiome-based products.

 

11.30
How to Harness Novel Microbiome Opportunities and Build a Robust IP Strategy

  • Megan Lyman IP, Regulatory and Product Development, AgTech Acclerator

Synopsis

  • What impact will microbiome discoveries have on future animal health products?
  • Understanding the evolving regulatory, trademark, and IP landscapes
  • What are the nuances and pitfalls within the animal microbiome to be aware of when developing a commercially successful product

12.00
Lunch & Networking

12.05

Where’s it All Heading? Managing Uncertainty and Creating a Long Strategy Within the Companion Animal Microbiome


Synopsis

Introduction and Purpose:
With market confidence of the microbiome still hinging on a handful of key human therapeutic applications, there are still huge scientific and product development challenges that need to be met before the microbiome becomes part of preventing disease in animal health.

13.00
Host-Microbiome Interactions: Influencing the Function of the Dog Microbiome Through Nutiriton to Impact Health and Behaviour

13.30
Mining Microbiome Data to Create Better Diagnostics to Identify and Manage Chronic Health Conditions in Companion Animals

Synopsis

  • The value of building large datasets
  • Integrating health and microbiome data
  • The predictive capability of the gut microbiome
  • Using microbiome-based diagnostics to develop interventions to manage common health conditions
  • Manipulating the microbiome with foods and therapies

14.00
Potential Prophylactic and Therapeutic Probiotics in Companion Animals

  • Aaron Ericsson Director, MU Metagenomics Center, University of Missouri

Synopsis

• Discussing ongoing data that suggests Lactobacillus spp. alleviates signs of stress through the gut-brain axis
• Outlining the use of simple probiotic administration as an alternative to traditional pharmaceutical intervention
• Exploring how probiotics may treat chronic respiratory disease including secondary pneumonia, chronic bronchitis, and asthma

14.30
The Equine Microbiome Project: Building a Long Term Future to Study Equine Health

  • Amy Biddle Assistant Professor, University of Delaware

Synopsis

  • The equine gastrointestinal system is uniquely sensitive to dysbiosis.
  • Diet and metabolic state are major drivers of microbiome structure and function for horses.
  • Since 2015, the Equine Microbiome Project has leveraged the interest of horse owners to provide samples, establishing a growing 16S rRNA sequence and metadata database.

15.00
Chair’s Closing Remarks

15.10
Close of inaugural Microbiome Animal Health Summit 2018