Generic Medications Used to Treat ADHD

Prescription pills spill out of medication bottle on a counter.

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Although many brand-name drugs are available to help treat ADHD (attention-deficit/hyperactivity disorder), generic alternatives can be more affordable. For this reason, many insurance providers even require them. Here's the rundown on a few of the most common generic medications used to treat ADHD.

Common ADHD Medications

Common ADHD medications fall into two main categories: stimulants and non-stimulants.

Stimulant ADHD Medications

Stimulant ADHD drugs work by slowly and steadily increasing the level of dopamine in the brain, producing positive effects related to movement and attention. Here are some of the most common ADHD stimulants, with their generics listed in parenthesis:

  • Adderall and Adderall XR (amphetamine-dextroamphetamine or amphetamine/dextroamphetamine salts)
  • Concerta (methylphenidate)
  • Daytrana (methylphenidate)
  • Dexedrine (dextroamphetamine)
  • Dyanavel XR (amphetamine)
  • Focalin and Focalin XR (dexmethylphenidate)
  • Metadate CD (methylphenidate)
  • Methylin and Methylin ER (methylphenidate)
  • Ritalin and Ritalin LA (methylphenidate)
  • Quillivant XR (methylphenidate)
  • Vyvanse (lisdexamfetamine)

The XR, ER, and LA designations indicate extended-release preparations.

Non-Stimulant ADHD Medications

Non-stimulant ADHD medications are typically prescribed for ADHD treatment when someone does not respond well to stimulant drugs. Non-stimulants include:

  • Intuniv (guanfacine)
  • Kapvay (clonidine)
  • Strattera (atomoxetine)
  • Qelbree (viloxazine)

Cost of Brand Name vs. Generic ADHD Drugs

The FDA reports that the cost of generic medications is typically around 85% less than that of brand-name options when multiple generics for the same drug are available.  In many instances, switching to generic medications can save hundreds or thousands of dollars on ADHD treatment each year.

Additionally, although it may be more convenient to take extended-release versions of ADHD drugs because fewer doses are needed, these formulations are generally more expensive. So, you may save money by using shorter-acting generics instead.

Medication costs also vary by pharmacy and insurance coverage. Some insurance companies authorize only brand-name drugs; others, generics.

Are Generic ADHD Drugs Effective?

Every generic medication goes through the same degree of scrutiny and approval process by the Food and Drug Administration (FDA). The agency states, "A generic medicine works in the same way and provides the same clinical benefit as its brand-name version." The generic must have the same safety, strength, quality, performance, and intended use.

Notably, the FDA withdrew approval of two generic versions of Concerta (methylphenidate hydrochloride) extended-release (ER) capsules because they failed to demonstrate the same therapeutic effect as the brand-name version.

Changing ADHD Medications

Like any other medication, a generic drug might produce different reactions in some people than the brand-name equivalent (or vice versa). Therefore, it's important to pay attention to any changes when switching ADHD medications.

Bring up anything you notice—including side effects—to your healthcare provider so they can adjust your dosage or type of medication. ADHD is a highly individual condition that requires individualized treatment.

ADHD Medication Side Effects

Some of the most common ADHD medication side effects include decreased appetite, trouble sleeping, anxiety, upset stomach, and changes in blood pressure or heart rate. If these effects don't go away after a couple of weeks or are bothersome, talk with the prescribing physician about your options.

Payment Support for ADHD Medications

Your physician might offer the option of a generic equivalent to lower the cost of your ADHD medications. Many large pharmacy retailers offer value formularies—lists of medication alternatives that can be prescribed at lower cost. Prescription assistance programs are also available in many communities.

In Summary

Treating ADHD with medications often requires patience and open conversations with your healthcare provider. Discuss any concerns regarding the cost, side effects, and effectiveness of your ADHD treatment to help them determine the best treatment for you.

5 Sources
Verywell Mind uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.
  1. National Institute on Drug Abuse. Stimulant ADHD medications: methylphenidate and amphetamines.

  2. Shier AC, Reichenbacher T, Ghuman HS, Ghuman JK. Pharmacological treatment of attention deficit hyperactivity disorder in children and adolescents: clinical strategies. J Cent Nerv Syst Dis. 2013;5:1-17. doi:10.4137/JCNSD.S6691

  3. Food and Drug Administration. Generic drug facts.

  4. Food and Drug Administration. Methylphenidate hydrochloride extended release tablets (generic Concerta) made by Mallinckrodt and Kudco.

  5. Cleveland Clinic. ADHD medication.

By Michael Bihari, MD
Michael Bihari, MD, is a board-certified pediatrician, health educator, and medical writer, and president emeritus of the Community Health Center of Cape Cod.