Stress Management What To Know About Ashwagandha For Stress By Brina Patel Brina Patel Brina Patel is a freelance writer from Sacramento, California. Prior to writing full-time, she worked as an applied behavior analysis therapist for children on the autism spectrum. She leverages her own experiences researching emotions, as well as her personal challenges with chronic illness and anxiety, in her storytelling, with the hope of inspiring others to take better charge of their overall wellness and understand themselves on a deeper level. Learn about our editorial process Updated on November 22, 2022 Medically reviewed Verywell Mind articles are reviewed by board-certified physicians and mental healthcare professionals. Medical Reviewers confirm the content is thorough and accurate, reflecting the latest evidence-based research. Content is reviewed before publication and upon substantial updates. Learn more. by Ivy Kwong, LMFT Medically reviewed by Ivy Kwong, LMFT Ivy Kwong, LMFT, is a psychotherapist specializing in relationships, love and intimacy, trauma and codependency, and AAPI mental health. Learn about our Medical Review Board Print Azay photography / Getty Images Table of Contents View All Table of Contents Introduction Stress-Related Health Benefits of Ashwagandha Possible Side Effects Contraindications Dosage And Preparation What To Look For Other Questions A Word From Verywell Close Introduction Ashwagandha (Withania somnifera) is an evergreen shrub part of the nightshade family. It grows in regions of Africa and Asia and may be referred to as “Indian ginseng” or “winter cherry.” Ashwagandha root is most commonly used as a medicinal herb to reduce stress, but its effectiveness is not entirely proven. Stress-Related Health Benefits of Ashwagandha Ashwagandha has been used for thousands of years in Ayurveda, a form of traditional Indian medicine. However, it has only recently entered the mainstream and has been investigated in clinical trials for efficacy. Many scientists consider it an adaptogen, meaning it helps the body to cope with stress more effectively. Here are some of its stress-related health benefits. Herbal Remedies for OCD and Anxiety Disorders Emotional Stress Research has demonstrated ashwagandha’s efficacy in alleviating many common health challenges, with stress being the most robustly studied. One finding observed that ashwagandha reduced stress in participants by moderating the hypothalamus-pituitary-adrenal axis, a major player in our mood and stress levels. Another study had 250 participants take either 250 or 600 milligrams of ashwagandha. After eight weeks of supplementing with the herb, participants reported lower stress levels and also exhibited decreased levels of cortisol when compared to a placebo group. Though these findings show promise, future research is needed to determine ashwagandha’s efficacy in stress reduction. Sleep Many people with chronic stress may also report difficulty falling or staying asleep. Ashwagandha has been advantageous in improving sleep quality. One study found that among adults with insomnia especially, supplementing with the herb demonstrated marked improvement in their sleep. Cognition Furthermore, stress can affect an individual’s attentiveness. Ashwagandha can positively impact memory and focus. In a study among 130 adults aged 20-55, supplementing with the herb for 90 consecutive days demonstrated improved recall memory and lower error rates on recalling patterns. Type 2 Diabetes Emotional stress can also impact one’s physical well-being through a variety of common chronic illnesses, such as diabetes. Individuals with type 2 diabetes may benefit from supplementing with ashwagandha. One study found that it significantly lowered blood sugar and hemoglobin A1c levels. It also reduced lipid levels, insulin levels, and markers of oxidative stress, without posing any additional safety concerns. Possible Side Effects Ashwagandha is safe for most individuals, however, since research is still in its infancy, long-term effects are unknown. Common side effects of ingesting too much ashwagandha include nausea, headaches, diarrhea, and drowsiness. Contraindications Individuals with certain medical conditions or taking other pharmaceutical medications or supplements should use caution before taking ashwagandha. Due to ashwagandha’s reported increase in testosterone levels, those with hormone-sensitive prostate cancer should avoid supplementation. Furthermore, research has shown that ashwagandha can impact thyroid hormone levels. Those with thyroid conditions should speak with their physician before starting ashwagandha supplements. Most clinical trials have found ashwagandha supplementation to be safe. However, there have been instances of liver injury 2-12 weeks after starting the supplement, though these cases are extremely rare. In most cases, the injury subsided within 3 months of supplement cessation. As with any change to your supplement or medication regimen, consult with your doctor before adding ashwagandha to your wellness routine. If you believe you are experiencing adverse effects from ashwagandha, seek medical treatment immediately. Dosage And Preparation Most people take ashwagandha in capsule, gummy, tea, or powder form. Though there is no standard dosage, studies have shown 125 mg-600 mg daily to be safe for healthy adults. You can take capsules and gummies with or without food. Ashwagandha powder can be mixed into water or smoothies, or even baked into foods. It’s best to start off with a lower dose, and work your way up as you notice your body’s reaction to ashwagandha. What To Look For Bear in mind that ashwagandha supplements have not been regulated by the FDA. However, if you purchase supplements marked “organic,” this ensures that over 95% of the ingredients are organic. It’s important that the ashwagandha you use has independent third-party certification marked on its bottle. This indicated that the company is executing the best practices regarding testing, production, and supply chain. GMPs (Good Manufacturing Practices) and FSMA (Food Safety Modernization Act) are important certifications to look for. Other Questions What’s the best time of day to take ashwagandha? You can take it at any time of the day that is convenient for you. Due to its calming effects, some people prefer taking it prior to bedtime. How long will ashwagandha remain in my system? There are two types of compounds in ashwagandha—fat-soluble and water-soluble. The water-soluble compounds leave your body between 2-3 days, while the fat-soluble ones may take a month to leave your body. Can children take ashwagandha? Few studies have studied ashwagandha’s impact on children, and little research has been conducted on children in recent years. You should speak to your child’s physician prior to starting your child on ashwagandha supplements. Can pregnant women take ashwagandha? Research on ashwagandha’s impact on pregnant women has been mixed. One study found that up to 2,000 mg of ashwagandha is safe for pregnant women. However, another report pointed out the potential toxicity brought about by herbal medicine, with additional research needed to determine ashwagandha’s effects on pregnant women. 7 Best Herbs for Memory and Brain Health A Word From Verywell While there are several studies showing the effectiveness of ashwagandha for stress and other conditions, it is still not considered clinically proven on a wider scale, and more research is needed before conclusive claims about stress regulation can be made. For this reason, you should always consult with your physician and/or psychiatrist prior to incorporating a new supplement into your routine, as many herbs can interfere with certain medications. 18 Effective Stress Relief Strategies 13 Sources Verywell Mind uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy. Tandon N, Yadav SS. Safety and clinical effectiveness of Withania Somnifera (Linn.) Dunal root in human ailments. J Ethnopharmacol. 2020 Jun 12;255:112768. doi: 10.1016/j.jep.2020.112768. Lopresti AL, Smith SJ, Malvi H, Kodgule R. An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract: A randomized, double-blind, placebo-controlled study. Medicine (Baltimore). 2019 Sep;98(37):e17186. doi: 10.1097/MD.0000000000017186. Salve J, Pate S, Debnath K, Langade D. Adaptogenic and Anxiolytic Effects of Ashwagandha Root Extract in Healthy Adults: A Double-blind, Randomized, Placebo-controlled Clinical Study. Cureus. 2019 Dec 25;11(12):e6466. doi: 10.7759/cureus.6466. Cheah KL, Norhayati MN, Husniati Yaacob L, Abdul Rahman R. Effect of Ashwagandha (Withania somnifera) extract on sleep: A systematic review and meta-analysis. PLoS One. 2021 Sep 24;16(9):e0257843. doi: 10.1371/journal.pone.0257843. Gopukumar K, Thanawala S, Somepalli V, Rao TSS, Thamatam VB, Chauhan S. Efficacy and Safety of Ashwagandha Root Extract on Cognitive Functions in Healthy, Stressed Adults: A Randomized, Double-Blind, Placebo-Controlled Study. Evid Based Complement Alternat Med. 2021 Nov 30;2021:8254344. doi: 10.1155/2021/8254344. Wong H, Singh J, Go RM, Ahluwalia N, Guerrero-Go MA. The Effects of Mental Stress on Non-insulin-dependent Diabetes: Determining the Relationship Between Catecholamine and Adrenergic Signals from Stress, Anxiety, and Depression on the Physiological Changes in the Pancreatic Hormone Secretion. Cureus. 2019 Aug 24;11(8):e5474. doi: 10.7759/cureus.5474. Durg S, Bavage S, Shivaram SB. Withania somnifera (Indian ginseng) in diabetes mellitus: A systematic review and meta-analysis of scientific evidence from experimental research to clinical application. Phytother Res. 2020 May;34(5):1041-1059. doi: 10.1002/ptr.6589. Memorial Sloan Kettering Cancer Center. Ashwagandha. Lopresti AL, Drummond PD, Smith SJ. A Randomized, Double-Blind, Placebo-Controlled, Crossover Study Examining the Hormonal and Vitality Effects of Ashwagandha ( Withania somnifera) in Aging, Overweight Males. Am J Mens Health. 2019 Mar-Apr;13(2):1557988319835985. doi: 10.1177/1557988319835985. Sharma AK, Basu I, Singh S. Efficacy and Safety of Ashwagandha Root Extract in Subclinical Hypothyroid Patients: A Double-Blind, Randomized Placebo-Controlled Trial. J Altern Complement Med. 2018 Mar;24(3):243-248. doi: 10.1089/acm.2017.0183. National Library of Medicine. Ashwagandha. Prabu PC, Panchapakesan S. Prenatal developmental toxicity evaluation of Withania somnifera root extract in Wistar rats. Drug Chem Toxicol. 2015 Jan;38(1):50-6. doi: 10.3109/01480545.2014.900073. Illamola SM, Amaeze OU, Krepkova LV, Birnbaum AK, Karanam A, Job KM, Bortnikova VV, Sherwin CMT, Enioutina EY. Use of Herbal Medicine by Pregnant Women: What Physicians Need to Know. Front Pharmacol. 2020 Jan 9;10:1483. doi: 10.3389/fphar.2019.01483. By Brina Patel Brina Patel is a freelance writer from Sacramento, California. Prior to writing full-time, she worked as an applied behavior analysis therapist for children on the autism spectrum. She leverages her own experiences researching emotions, as well as her personal challenges with chronic illness and anxiety, in her storytelling, with the hope of inspiring others to take better charge of their overall wellness and understand themselves on a deeper level. See Our Editorial Process Meet Our Review Board Share Feedback Was this page helpful? Thanks for your feedback! What is your feedback? Helpful Report an Error Other Submit